Cutaneous manifestations of COVID-19 in a tertiary COVID-19 referral hospital in the PhilippinesCapsule Summary

• Main Authors: Cyrene C. Tan, MD (Author), Belen L. Dofitas, MD, FPDS (Author), Ma. Lorna F. Frez, MD, FPDS (Author), Celina Daia D. Yap, MD (Author), Jeanie Karen K. Uy, MD (Author), Cynthia P. Ciriaco-Tan, MD, FPDS (Author)
• Format: Book
• Published: Elsevier, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

Background: Reports on COVID-19 skin manifestations and associated clinical outcomes are limited. Like viral diseases, cutaneous findings may be present and can help in confirmation and prognostication among those suspected or diagnosed with COVID-19. Objective: To determine COVID-19 cutaneous manifestations and their association with disease severity and course. Methods: This study was conducted in a designated COVID-19 referral hospital from January 1 to March 31, 2021. Skin manifestations recorded from January 1 to February 17 were retrospectively gathered. Reports from February 18 to March 31 were prospectively collected using a dermatologic checklist which was incorporated into all official medical records. Results: A total of 507 confirmed patients with COVID-19 were included. COVID-19 skin signs were detected in 39 patients (7.7%). Morbilliform lesions were most common. Skin signs were significantly associated with severe or critical cases (odds ratio, 3.4; 95% CI, 1.3-8.7) and mortality (relative risk, 2.9; 95% CI, 2.0-4.2). Limitations: Underestimation of prevalence of COVID-19 skin signs due to exclusion of outpatient and discharged patients and the subjective assessment in the retrospective part. Conclusion: Cutaneous signs were significantly associated with severe/critical COVID-19 as well as death among 507 hospitalized patients in a Philippine COVID-19 referral hospital.

Item Description

2666-3287
10.1016/j.jdin.2022.01.007