Janus Kinase (JAK) Inhibitors in Rheumatoid Arthritis

Janus kinase (JAK) and signal transducer and activator of transcription (STAT) signalling has been established to have pathophysiological role in multiple disease states, such as myeloproliferative neoplasms, rheumatoid arthritis, inflammatory bowel disease and multiple immune-driven dermatological...

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Bibliographic Details
Main Authors: Vishal R. Tandon (Author), Annil Mahajan (Author)
Format: Book
Published: Dr. Annil Mahajan, 2022-07-01T00:00:00Z.
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245 0 0 |a Janus Kinase (JAK) Inhibitors in Rheumatoid Arthritis 
260 |b Dr. Annil Mahajan,   |c 2022-07-01T00:00:00Z. 
500 |a 0972-1177 
520 |a Janus kinase (JAK) and signal transducer and activator of transcription (STAT) signalling has been established to have pathophysiological role in multiple disease states, such as myeloproliferative neoplasms, rheumatoid arthritis, inflammatory bowel disease and multiple immune-driven dermatological diseases etc. JAK inhibitors are low-molecular-weight compounds, which exert anti-rheumatic effects by suppressing the action of JAK, an intracellular tyrosine kinase. JAK inhibitors are useful mainly in a variety of cases, including patients who inadequately responded to treatment with methotrexate and/or DMARDs. 
546 |a EN 
690 |a Janus kinase 
690 |a Rheumatoid arthritis 
690 |a Janus kinase (JAK) inhibitors 
690 |a Tofacitinib 
690 |a Baricitinib 
690 |a Upadacitinib 
690 |a Medicine (General) 
690 |a R5-920 
690 |a Internal medicine 
690 |a RC31-1245 
655 7 |a article  |2 local 
786 0 |n JK Science, Vol 24, Iss 3 (2022) 
787 0 |n https://journal.jkscience.org/index.php/JK-Science/article/view/134 
787 0 |n https://doaj.org/toc/0972-1177 
856 4 1 |u https://doaj.org/article/a3fee2772e664a529db7c67ff838d6b6  |z Connect to this object online.