Clinical feature-related single-base substitution sequence signatures identified with an unsupervised machine learning approach
Abstract Background Mutation processes leave different signatures in genes. For single-base substitutions, previous studies have suggested that mutation signatures are not only reflected in mutation bases but also in neighboring bases. However, because of the lack of a method to identify features of...
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Main Authors: | Hongchen Ji (Author), Junjie Li (Author), Qiong Zhang (Author), Jingyue Yang (Author), Juanli Duan (Author), Xiaowen Wang (Author), Ben Ma (Author), Zhuochao Zhang (Author), Wei Pan (Author), Hongmei Zhang (Author) |
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Format: | Book |
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BMC,
2021-12-01T00:00:00Z.
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