An Advanced Automated Patch Clamp Protocol Design to Investigate Drug-Ion Channel Binding Dynamics
Standard high throughput screening projects using automated patch-clamp instruments often fail to grasp essential details of the mechanism of action, such as binding/unbinding dynamics and modulation of gating. In this study, we aim to demonstrate that depth of analysis can be combined with acceptab...
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Main Authors: | Peter Lukacs (Author), Krisztina Pesti (Author), Mátyás C. Földi (Author), Katalin Zboray (Author), Adam V. Toth (Author), Gábor Papp (Author), Arpad Mike (Author) |
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Format: | Book |
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Frontiers Media S.A.,
2021-09-01T00:00:00Z.
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