Implications in dental treatment during the use of antiresorptive drugs - a literature review

Introduction: Antiresorptive drugs such as bisphosphonates and denosumab are crucial for treating osteoporosis, metastatic bone disease, and hypercalcemia by inhibiting osteoclast function. They can lead to medication-related osteonecrosis of the jaw (MRONJ) following invasive dental procedures, req...

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Main Authors: Aleksandra Dziewulska (Author), Weronika Kiełt (Author), Julia Kozłowska (Author), Gabriela Broniec (Author), Barbara Wajdowicz (Author), Aleksandra Kudła (Author), Rozalia Czapiewska (Author), Aleksandra Wróbel (Author), Laura Pacek (Author), Klaudia Kowalska (Author)
Format: Book
Published: Kazimierz Wielki University, 2024-10-01T00:00:00Z.
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Summary:Introduction: Antiresorptive drugs such as bisphosphonates and denosumab are crucial for treating osteoporosis, metastatic bone disease, and hypercalcemia by inhibiting osteoclast function. They can lead to medication-related osteonecrosis of the jaw (MRONJ) following invasive dental procedures, requiring careful management to mitigate potential adverse effects.   Purpose of work: Synthesis of knowledge about the impact of taking antiresorptive drugs on aspects of dental treatment.   Materials and methods: Materials used in this study were found in the PubMed and Google Scholar database, using the following key words "antiresorptives", "bisphosphonates", "dental treatment", "osteonecrosis of the jaw"  Summary: Antiresorptive drugs like bisphosphonates and denosumab are essential for managing osteoporosis and other bone diseases but pose challenges in dental care, notably with risks such as medication-related osteonecrosis of the jaw (MRONJ). These medications influence treatment strategies across orthodontics, implantology, periodontal therapy, and endodontics, necessitating careful management to balance therapeutic benefits with potential dental complications. 
Item Description:10.12775/JEHS.2024.69.55356
2391-8306