Identification of genetic variants for clinical management of familial colorectal tumors

• Main Authors: Mev Dominguez-Valentin (Author), Sigve Nakken (Author), Hélène Tubeuf (Author), Daniel Vodak (Author), Per Olaf Ekstrøm (Author), Anke M. Nissen (Author), Monika Morak (Author), Elke Holinski-Feder (Author), Alexandra Martins (Author), Pål Møller (Author), Eivind Hovig (Author)
• Format: Book
• Published: BMC, 2018-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The genetic mechanisms for families who meet the clinical criteria for Lynch syndrome (LS) but do not carry pathogenic variants in the mismatch repair (MMR) genes are still undetermined. We aimed to study the potential contribution of genes other than MMR genes to the biological...