The Pancreatic β-Cell: The Perfect Redox System

• Main Authors: Petr Ježek (Author), Blanka Holendová (Author), Martin Jabůrek (Author), Jan Tauber (Author), Andrea Dlasková (Author), Lydie Plecitá-Hlavatá (Author)
• Format: Book
• Published: MDPI AG, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pancreatic β-cell insulin secretion, which responds to various secretagogues and hormonal regulations, is reviewed here, emphasizing the fundamental redox signaling by NADPH oxidase 4- (NOX4-) mediated H₂O₂ production for glucose-stimulated insulin secre...