Hydroquinone 5-<i>O</i>-Cinnamoyl Ester of Renieramycin M Suppresses Lung Cancer Stem Cells by Targeting Akt and Destabilizes c-Myc

• Main Authors: Nattamon Hongwiangchan (Author), Nicharat Sriratanasak (Author), Duangdao Wichadakul (Author), Nithikoon Aksorn (Author), Supakarn Chamni (Author), Pithi Chanvorachote (Author)
• Format: Bog
• Udgivet: MDPI AG, 2021-10-01T00:00:00Z.
• Fag: article
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Cancer stem cells (CSCs) are distinct cancer populations with tumorigenic and self-renewal abilities. CSCs are drivers of cancer initiation, progression, therapeutic failure, and disease recurrence. Thereby, novel compounds targeting CSCs offer a promising way to control cancer. In this study, the h...