Cover Image

Highly Efficient Synthesis of 1,4-Disubstituted 1,2,3-Triazole Derivatives under Ultrasonic Irradiation, Evaluation of Vasorelaxant Activities

1,4-Disubstituted 1,2,3-Triazole derivatives are exciting pharmacophores with a wide range of biological activities, including anticancer, antituberculosis, antifungal, antibacterial, and anti-HIV. Due to their diverse uses, many efforts have been made to synthesize these valuable medicinal scaffold...

Full description

Saved in:

Bibliographic Details
Main Authors:	Sakineh Ebrahimpourmoghaddam (Author), Maryam Motevasel (Author), Saghar Mowlazadeh Haghighi (Author), Azar Purkhosrow (Author), Hashem Sharghi (Author), Ali Khalafi-Nezhad (Author), Elahe Sattarinezhad (Author)
Format:	Book
Published:	Shiraz University of Medical Sciences, 2024-03-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Synthesis, Evaluation of Vasorelaxant Activity, and Molecular Docking of Pyranopyrazole Derivatives as Calcium Channel Blockers
by: Saghar Mowlazadeh Haghighi, et al.
Published: (2023)

Synthesis and Evaluation of (1,4-Disubstituted)-1,2,3-triazoles as Estrogen Receptor Beta Agonists
by: Edward A. Wetzel, et al.
Published: (2022)

Design, synthesis, conformational analysis, and biological activity of Cα1-to-Cα6 1,4- and 4,1-disubstituted 1H-[1,2,3]triazol-1-yl-bridged oxytocin analogues
by: Francesca Nuti, et al.
Published: (2023)

Discovery of Icotinib-1,2,3-Triazole Derivatives as IDO1 Inhibitors
by: Long-fei Mao, et al.
Published: (2020)

Discovery of Novel 1,2,3-triazole Derivatives as IDO1 Inhibitors
by: Xixi Hou, et al.
Published: (2022)

Synthesis Of 2-Benzamidomethyl-5-Substituted Amino-1,3,4-Thiadiazoles-2,5-Disubstituted 1,3,4-Oxadiazole and 4,5-Disubstituted 1,2,4-Triazole-3-Thiol
by: K. M. Daoud, et al.
Published: (2012)

An Overview of 1,2,3-triazole-Containing Hybrids and Their Potential Anticholinesterase Activities
by: Shah Alam Khan, et al.
Published: (2023)

Synthesis and Antioxidant Properties of Novel 1,2,3-Triazole-Containing Nitrones
by: Dimitra Hadjipavlou-Litina, et al.
Published: (2022)

Synthesis and Antitumor Activity of Erlotinib Derivatives Linked With 1,2,3-Triazole
by: Peng Deng, et al.
Published: (2022)

A Review on 1,2,3 - Triazole & Piperazine Derivatives with Various Biological Activities
by: C Geethapriya Loganathan, et al.
Published: (2023)

Investigation of 1,4-Substituted 1,2,3-Triazole Derivatives as Antiarrhythmics: Synthesis, Structure, and Properties
by: Elena O. Shestakova, et al.
Published: (2022)

Structural Study of a La(III) Complex of a 1,2,3-Triazole Ligand with Antioxidant Activity
by: Mauricio Alcolea Palafox, et al.
Published: (2023)

Design and synthesis of cabotegravir derivatives bearing 1,2,3-triazole and evaluation of anti-liver cancer activity
by: Huaxia Xie, et al.
Published: (2023)

Synthesis and Biological Evaluation of 1,2,3-Triazole Tethered Thymol-1,3,4-Oxadiazole Derivatives as Anticancer and Antimicrobial Agents
by: Abdulraheem S. A. Almalki, et al.
Published: (2021)

Crystallography, in Silico Studies, and In Vitro Antifungal Studies of 2,4,5 Trisubstituted 1,2,3-Triazole Analogues
by: Katharigatta N. Venugopala, et al.
Published: (2020)

Selective inhibition of carbonic anhydrase IX by sulphonylated 1,2,3-triazole incorporated benzenesulphonamides capable of inducing apoptosis
by: Kiran Siwach, et al.
Published: (2022)

Synthesis, Characterization, ADME Study and Antimicrobial Evaluation of New 1,2,3-triazole Derivatives of 2-phenyl benzimidazole.
by: Asmaa Adnan Abdulnabi, et al.
Published: (2023)

Discovery of New Boswellic Acid Hybrid 1<i>H</i>-1,2,3-Triazoles for Diabetic Management: In Vitro and In Silico Studies
by: Najeeb Ur Rehman, et al.
Published: (2023)

Exploration of 5-cyano-6-phenylpyrimidin derivatives containing an 1,2,3-triazole moiety as potent FAD-based LSD1 inhibitors
by: Liying Ma, et al.
Published: (2020)

Novel 1,2,3-Triazole-sulphadiazine-ZnO Hybrids as Potent Antimicrobial Agents against Carbapenem Resistant Bacteria
by: Faizah S. Aljohani, et al.
Published: (2022)

Discovery of a Series of Theophylline Derivatives Containing 1,2,3-Triazole for Treatment of Non-Small Cell Lung Cancer
by: Jiahui Ye, et al.
Published: (2021)

Synthesis of 1,2,3-Triazole-Containing Methoxylated Cinnamides and Their Antileishmanial Activity against the <i>Leishmania braziliensis</i> Species
by: Fabíola Suelen dos Santos, et al.
Published: (2023)

In Vitro and In Vivo Antiviral Studies of New Heteroannulated 1,2,3-Triazole Glycosides Targeting the Neuraminidase of Influenza A Viruses
by: Omnia Kutkat, et al.
Published: (2022)

Synthesis, computational study and biological evaluation of 9-acridinyl and 1-coumarinyl-1,2,3-triazole-4-yl derivatives as topoisomerase II inhibitors
by: Gehan A. Abdel-Hafez, et al.
Published: (2022)

Synthesis and biological evaluation of novel 1,2,3-triazole hybrids of cabotegravir: identification of potent antitumor activity against lung cancer
by: Yajie Guo, et al.
Published: (2023)

1,2,3-Triazole-Containing Compounds as Anti-Lung Cancer Agents: Current Developments, Mechanisms of Action, and Structure-Activity Relationship
by: Ting Liang, et al.
Published: (2021)

Investigation of the Mechanisms of Cytotoxic Activity of 1,3-Disubstituted Thiourea Derivatives
by: Paulina Strzyga-Łach, et al.
Published: (2021)

Synthesis of a new series of 3-functionalised-1-phenyl-1,2,3-triazole sulfamoylbenzamides as carbonic anhydrase I, II, IV and IX inhibitors
by: Baijayantimala Swain, et al.
Published: (2019)

Design, synthesis, and apoptotic antiproliferative action of new 1,2,3-triazole/1,2,4-oxadiazole hybrids as dual EGFR/VEGFR-2 inhibitors
by: Mohamed A. Mahmoud, et al.
Published: (2024)

Novel hybrids of 1,2,3-triazole-benzoxazole: design, synthesis, and assessment of DprE1 enzyme inhibitors using fluorometric assay and computational analysis
by: Manisha Singh, et al.
Published: (2024)

New potent steroid sulphatase inhibitors based on 6-(1-phenyl-1H-1,2,3-triazol-4-yl)naphthalen-2-yl sulphamate derivatives
by: Olga Ciupak, et al.
Published: (2021)

Synthesis, characterization, antimicrobial, and pharmacological evaluation of some 2, 5-disubstituted sulfonyl amino 1,3,4-oxadiazole and 2-amino-disubstituted 1,3,4-thiadiazole derivatives
by: Dilipkumar Pal, et al.
Published: (2014)

New 1,2,3-triazole linked ciprofloxacin-chalcones induce DNA damage by inhibiting human topoisomerase I& II and tubulin polymerization
by: Hamada H. H. Mohammed, et al.
Published: (2022)

Phenylpyrazolone-1,2,3-triazole Hybrids as Potent Antiviral Agents with Promising SARS-CoV-2 Main Protease Inhibition Potential
by: Arafa Musa, et al.
Published: (2023)

Anti-Tick-Borne Encephalitis Virus Activity of Novel Uridine Glycoconjugates Containing Amide or/and 1,2,3-Triazole Moiety in the Linker Structure
by: Gabriela Brzuska, et al.
Published: (2020)

Novel 1,2,3-triazole-aurone hybrids as cathepsin B inhibitors: One-pot synthesis, anti-proliferative, and drug modeling studies
by: Bhavna Saroha, et al.
Published: (2022)

Synthesis of 2-(6-substituted quinolin-4-yl)-1-(4-aryl-1H-1,2,3-triazol-1-yl) propan-2-ol as potential antifungal and antitubercular agents
by: Abhijit Shinde, et al.
Published: (2023)

Synthesis, characterization and utilization of a new series of 1,2,3-triazole derivatives to neutralize some toxic activities of Bothrops jararaca snake venom
by: Nayanna de Mello Amorim, et al.
Published: (2023)

The Search for New Antibacterial Agents among 1,2,3-Triazole Functionalized Ciprofloxacin and Norfloxacin Hybrids: Synthesis, Docking Studies, and Biological Activity Evaluation
by: Halyna Hryhoriv, et al.
Published: (2021)

Aniline Derivatives Containing 1-Substituted 1,2,3-Triazole System as Potential Drug Candidates: Pharmacokinetic Profile Prediction, Lipophilicity Analysis Using Experimental and In Silico Studies
by: Elwira Chrobak, et al.
Published: (2024)