Recurrent and novel fusions detected by targeted RNA sequencing as part of the diagnostic workflow of soft tissue and bone tumours

• Main Authors: Rafael Zago Baltazar (Author), Sofie Claerhout (Author), Sara Vander Borght (Author), Lien Spans (Author), Raphael Sciot (Author), Patrick Schöffski (Author), Daphne Hompes (Author), Friedl Sinnaeve (Author), Hazem Wafa (Author), Marleen Renard (Author), Mari FCM van den Hout (Author), Astrid Vernemmen (Author), Louis Libbrecht (Author), An‐Katrien De Roo (Author), Filomena Mazzeo (Author), Cédric van Marcke (Author), Karen Deraedt (Author), Claire Bourgain (Author), Isabelle Vanden Bempt (Author)
• Format: Bog
• Udgivet: Wiley, 2024-05-01T00:00:00Z.
• Fag: article
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Abstract The identification of gene fusions has become an integral part of soft tissue and bone tumour diagnosis. We investigated the added value of targeted RNA‐based sequencing (targeted RNA‐seq, Archer FusionPlex) to our current molecular diagnostic workflow of these tumours, which is based on fl...