Blood and bone marrow findings in tuberculosis in adults -A cross sectional study

Background: Tuberculosis is a major public health problem in India. Hematolgical changes have been studied with variable results. Aims and objectives: The present study was undertaken to know the prevalence of blood and bone marrow changes in tuberculosis. Methods: The peripheral blood and bone marr...

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Main Authors: S.R. Dafale (Author), R.Y. Chavan (Author), G.S. Pilli (Author), P.R. Malur (Author), H.B. Bannur (Author), S.S. Sangolli (Author), B.R. Hungund (Author), A.V. Joshi (Author)
Format: Book
Published: Al Ameen Medical College, 2012-10-01T00:00:00Z.
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Summary:Background: Tuberculosis is a major public health problem in India. Hematolgical changes have been studied with variable results. Aims and objectives: The present study was undertaken to know the prevalence of blood and bone marrow changes in tuberculosis. Methods: The peripheral blood and bone marrow changes were evaluated in hundred adult patients with tuberculosis, admitted at District Hospital, Belgaum and KLES Hospital and MRC were. Results: The peripheral blood findings seen were anemia, raised ESR, leukocytosis, neutrophilia, lymphocytosis, eosinophilia, leucopenia, thrombocytosis and thrombocytope-nia. The bone marrow changes seen were hypercellularity , myeloid hyperplasia , erythroid hyperplasia with megaloblastic changes and reactive plasmacytosis. Another interesting finding in bonemarrow was presence of granulomas which were seen in 5% of cases of which 1 case showed positivity for acid fast bacilli on Zeihl -Neelsen stain. Conclusion: The varied hematological findings observed in tuberculosis should prompt us to consider tuberculosis as one of the differential diagnosis in patients with hematological findings.
Item Description:0974-1143