Licochalcone B Induces ROS-Dependent Apoptosis in Oxaliplatin-Resistant Colorectal Cancer Cells via p38/JNK MAPK Signaling

• Main Authors: Ah-Won Kwak (Author), Woo-Keun Kim (Author), Seung-On Lee (Author), Goo Yoon (Author), Seung-Sik Cho (Author), Ki-Taek Kim (Author), Mee-Hyun Lee (Author), Yung Hyun Choi (Author), Jin-Young Lee (Author), Jin Woo Park (Author), Jung-Hyun Shim (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Licochalcone B (LCB) exhibits anticancer activity in oral cancer, lung cancer, and hepatocellular carcinoma cells. However, little is known about its antitumor mechanisms in human oxaliplatin-sensitive and -resistant colorectal cancer (CRC) cells. The purpose of the present study was to investigate...