Tripling the Bioavailability of Rosuvastatin Calcium Through Development and Optimization of an In-Situ Forming Nanovesicular System

• Main Authors: Ibrahim Elsayed (Author), Rania Moataz El-Dahmy (Author), Ahmed Hassen Elshafeey (Author), Nabaweya Abdelaziz Abd El Gawad (Author), Omaima Naim El Gazayerly (Author)
• 格式: 圖書
• 出版: MDPI AG, 2019-06-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

In situ forming nanovesicular systems (IFNs) were prepared and optimized to improve Rosuvastatin calcium (RC) oral bioavailability through increasing its solubility and dissolution rate. The IFN was composed of Tween^® 80 (T80), cetyl alcohol (CA), in addition to manni...