A review on regulation of DNA methylation during post-myocardial infarction

Myocardial infarction (MI) imposes a huge medical and economic burden on society, and cardiac repair after MI involves a complex series of processes. Understanding the key mechanisms (such as apoptosis, autophagy, inflammation, and fibrosis) will facilitate further drug development and patient treat...

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Main Authors: Wenqiang Han (Author), Wenxin Wang (Author), Qinhong Wang (Author), Kellina Maduray (Author), Li Hao (Author), Jingquan Zhong (Author)
Format: Book
Published: Frontiers Media S.A., 2024-02-01T00:00:00Z.
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100 1 0 |a Wenqiang Han  |e author 
700 1 0 |a Wenxin Wang  |e author 
700 1 0 |a Qinhong Wang  |e author 
700 1 0 |a Kellina Maduray  |e author 
700 1 0 |a Li Hao  |e author 
700 1 0 |a Jingquan Zhong  |e author 
700 1 0 |a Jingquan Zhong  |e author 
245 0 0 |a A review on regulation of DNA methylation during post-myocardial infarction 
260 |b Frontiers Media S.A.,   |c 2024-02-01T00:00:00Z. 
500 |a 1663-9812 
500 |a 10.3389/fphar.2024.1267585 
520 |a Myocardial infarction (MI) imposes a huge medical and economic burden on society, and cardiac repair after MI involves a complex series of processes. Understanding the key mechanisms (such as apoptosis, autophagy, inflammation, and fibrosis) will facilitate further drug development and patient treatment. Presently, a substantial body of evidence suggests that the regulation of epigenetic processes contributes to cardiac repair following MI, with DNA methylation being among the notable epigenetic factors involved. This article will review the research on the mechanism of DNA methylation regulation after MI to provide some insights for future research and development of related drugs. 
546 |a EN 
690 |a myocardial infarction 
690 |a DNA methylation 
690 |a inflammation 
690 |a autophagy 
690 |a proliferation 
690 |a fibrosis 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
655 7 |a article  |2 local 
786 0 |n Frontiers in Pharmacology, Vol 15 (2024) 
787 0 |n https://www.frontiersin.org/articles/10.3389/fphar.2024.1267585/full 
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