Striatal spine plasticity in Parkinson's Disease
Striatal dopamine (DA) denervation results in a significant loss of dendritic spines on medium spiny projection neurons in Parkinson's disease (PD). In 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated parkinsonian monkeys, spines contacted either by cortical or thalamic glutamatergic...
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| Format: | Book |
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Frontiers Media S.A.,
2010-12-01T00:00:00Z.
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