Prediction of Clinical Transporter‐Mediated Drug-Drug Interactions via Comeasurement of Pitavastatin and Eltrombopag in Human Hepatocyte Models
A structurally identifiable micro‐rate constant mechanistic model was used to describe the interaction between pitavastatin and eltrombopag, with improved goodness‐of‐fit values through comeasurement of pitavastatin and eltrombopag. Transporter association and dissociation rate constants and passive...
Saved in:
Main Authors: | Simon J. Carter (Author), Bhavik Chouhan (Author), Pradeep Sharma (Author), Michael J. Chappell (Author) |
---|---|
Format: | Book |
Published: |
Wiley,
2020-04-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Evaluation of the Pharmacokinetic Drug-Drug Interaction between Micronized Fenofibrate and Pitavastatin in Healthy Volunteers
by: Hae Won Lee, et al.
Published: (2020) -
Transporter-Mediated Drug-Drug Interactions with Oral Antidiabetic Drugs
by: Jörg König, et al.
Published: (2011) -
Role of Hepatocyte Transporters in Drug-Induced Liver Injury (DILI)-In Vitro Testing
by: Péter Tátrai, et al.
Published: (2022) -
Rifampin Regulation of Drug Transporters Gene Expression and the Association of MicroRNAs in Human Hepatocytes
by: Eric A Benson, et al.
Published: (2016) -
Renal drug transporters and their significance in drug-drug interactions
by: Jia Yin, et al.
Published: (2016)