Informational Odds Ratio: A Useful Measure of Epidemiologic Association in Environment Exposure Studies

The informational odds ratio (IOR) measures the post-exposure odds divided by the pre-exposure odds (ie, information gained after knowing exposure status). A desirable property of an adjusted ratio estimate is collapsibility (ie, the combined crude ratio will not change after adjusting for a variabl...

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Bibliographic Details
Main Authors: Jimmy T. Efird (Author), Suzanne Lea (Author), Amanda Toland (Author), Christopher J. Phillips (Author)
Format: Book
Published: SAGE Publishing, 2012-01-01T00:00:00Z.
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Summary:The informational odds ratio (IOR) measures the post-exposure odds divided by the pre-exposure odds (ie, information gained after knowing exposure status). A desirable property of an adjusted ratio estimate is collapsibility (ie, the combined crude ratio will not change after adjusting for a variable that is not a confounder). Adjusted traditional odds ratios (TORs) are not collapsible. In contrast, Mantel-Haenszel adjusted IORs generally are collapsible. IORs are a useful measure of disease association in environmental case-referent studies, especially when the disease is common in the exposed and/or unexposed groups.
Item Description:1178-6302
10.4137/EHI.S9236