Targeting interleukin-10 signalling for cancer immunotherapy, a promising and complicated task

• Main Authors: Guoying Ni (Author), Lu Zhang (Author), Xiaodan Yang (Author), Hejie Li (Author), Bowei Ma (Author), Shelley Walton (Author), Xiaolian Wu (Author), Jianwei Yuan (Author), Tianfang Wang (Author), Xiaosong Liu (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Interleukin 10 (IL-10) belongs to IL-10 family cytokines that are critical for maintaining the integrity of epithelial tissues, protecting pathogenic infection, and preventing excessive immune responses to damage self. Temporal IL-10 signaling blockade enhances vaccine-induced tumor regression by CD...