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Controlling the Solubility, Release Rate and Permeation of Riluzole with Cyclodextrins

Riluzole (RLZ), a sodium channel-blocking benzothiazole anticonvulsant BCS class II drug, is very slightly soluble in aqueous medium. To improve aqueous solubility and modulate dissolution rate and membrane permeability, complex formation of RLZ with two cyclodextrin, α-cyclodextrin (α-CD) and sulfo...

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Bibliographic Details
Main Authors:	Tatyana Volkova (Author), Olga Simonova (Author), German Perlovich (Author)
Format:	Book
Published:	MDPI AG, 2024-06-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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