Zika virus infection in pregnancy: Establishing a case definition for clinical research on pregnant women with rash in an active transmission setting.

• Main Authors: Ricardo Arraes de Alencar Ximenes (Author), Demócrito de Barros Miranda-Filho (Author), Elizabeth B Brickley (Author), Ulisses Ramos Montarroyos (Author), Celina Maria Turchi Martelli (Author), Thalia Velho Barreto de Araújo (Author), Laura C Rodrigues (Author), Maria de Fatima Pessoa Militão de Albuquerque (Author), Wayner Vieira de Souza (Author), Priscila Mayrelle da Silva Castanha (Author), Rafael F O França (Author), Rafael Dhália (Author), Ernesto T A Marques (Author), Microcephaly Epidemic Research Group (MERG) (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Defining cases of Zika virus (ZIKV) infection is a critical challenge for epidemiological research. Due to ZIKV's overlapping clinical features and potential immunologic cross-reactivity with other flaviviruses and the current lack of an optimal ZIKV-specific diagnostic assay, varying approache...