Atherogenic Dyslipidemias: Unmet Needs and the Therapeutic Potential of Emerging and Novel Approaches and Drugs

Innovative lipid-modifying agents are valuable resources to improve the control of atherogenic dyslipidemias and reduce the lipid-related residual cardiovascular risk of patients with intolerance or who are not fully responsive to a consolidated standard of care (statins plus ezetimibe). Moreover, s...

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Main Authors: Alessandra Romandini (Author), Damiano Baldassarre (Author), Stefano Genovese (Author), Stefano Capri (Author), Giulio Pompilio (Author), Marco Scatigna (Author), José Pablo Werba (Author)
Format: Book
Published: MDPI AG, 2023-01-01T00:00:00Z.
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001 doaj_a6c489c2bcc54f038b6446d5f3f4da1e
042 |a dc 
100 1 0 |a Alessandra Romandini  |e author 
700 1 0 |a Damiano Baldassarre  |e author 
700 1 0 |a Stefano Genovese  |e author 
700 1 0 |a Stefano Capri  |e author 
700 1 0 |a Giulio Pompilio  |e author 
700 1 0 |a Marco Scatigna  |e author 
700 1 0 |a José Pablo Werba  |e author 
245 0 0 |a Atherogenic Dyslipidemias: Unmet Needs and the Therapeutic Potential of Emerging and Novel Approaches and Drugs 
260 |b MDPI AG,   |c 2023-01-01T00:00:00Z. 
500 |a 10.3390/ph16020176 
500 |a 1424-8247 
520 |a Innovative lipid-modifying agents are valuable resources to improve the control of atherogenic dyslipidemias and reduce the lipid-related residual cardiovascular risk of patients with intolerance or who are not fully responsive to a consolidated standard of care (statins plus ezetimibe). Moreover, some of the upcoming compounds potently affect lipid targets that are thus far considered "unmodifiable". The present paper is a viewpoint aimed at presenting the incremental metabolic and cardiovascular benefits of the emerging lipid-modulating agents and real-life barriers, hindering their prescription by physicians and their assumption by patients, which need to be worked out for a more diffuse and appropriate drug utilization. 
546 |a EN 
690 |a atherogenic dyslipidemia 
690 |a lipid-modifying drugs 
690 |a cardiovascular disease 
690 |a drug intolerance 
690 |a Medicine 
690 |a R 
690 |a Pharmacy and materia medica 
690 |a RS1-441 
655 7 |a article  |2 local 
786 0 |n Pharmaceuticals, Vol 16, Iss 2, p 176 (2023) 
787 0 |n https://www.mdpi.com/1424-8247/16/2/176 
787 0 |n https://doaj.org/toc/1424-8247 
856 4 1 |u https://doaj.org/article/a6c489c2bcc54f038b6446d5f3f4da1e  |z Connect to this object online.