Phorbol 12, 13-dibutyrate-induced, protein kinase C-mediated contraction of rabbit bladder smooth muscle

• Main Authors: Tanchun eWang (Author), Derek M Kendig (Author), Danielle M Trappanese (Author), Elaine M Smolock (Author), Robert S Moreland (Author)
• Format: Book
• Published: Frontiers Media S.A., 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Contraction of bladder smooth muscle is predominantly initiated by M3 muscarinic receptor-mediated activation of the Gq/11-phospholipase C β-protein kinase C (PKC) and the G12/13-RhoGEF-Rho kinase (ROCK) pathways. However, these pathways and their downstream effectors are not well understood in blad...