The efficacy and safety of high-dose isoniazid-containing therapy for multidrug-resistant tuberculosis: a systematic review and meta-analysis

• Main Authors: Ming Zhou (Author), Ai-Mei Liu (Author), Xiao-Bing Yang (Author), Cui-Ping Guan (Author), Yan-An Zhang (Author), Mao-Shui Wang (Author), Ya-Li Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: Accumulating evidence are available on the efficacy of high-dose isoniazid (INH) for multidrug-resistant tuberculosis (MDR-TB) treatment. We aimed to perform a systematic review and meta-analysis to compare clinical efficacy and safety outcomes of high-dose INH- containing therapy agains...