Case series of cranial and spinal dysraphism

Neural tube defects (NTDs) are the second most common cause of congenital anomaly worldwide (cardiac anomalies is the first). The 3rd and 4th week of gestation is the critical period for neural tube development. Multiple genetic and environmental factors are known to cause the NTDs in a developing e...

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Main Authors: Gayathri Pandurangam (Author), D Nagajyothi (Author), Seethamsetty Saritha (Author), Asra Anjum (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2022-01-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Gayathri Pandurangam  |e author 
700 1 0 |a D Nagajyothi  |e author 
700 1 0 |a Seethamsetty Saritha  |e author 
700 1 0 |a Asra Anjum  |e author 
245 0 0 |a Case series of cranial and spinal dysraphism 
260 |b Wolters Kluwer Medknow Publications,   |c 2022-01-01T00:00:00Z. 
500 |a 2277-4025 
500 |a 2321-2780 
500 |a 10.4103/NJCA.NJCA_120_21 
520 |a Neural tube defects (NTDs) are the second most common cause of congenital anomaly worldwide (cardiac anomalies is the first). The 3rd and 4th week of gestation is the critical period for neural tube development. Multiple genetic and environmental factors are known to cause the NTDs in a developing embryo. We report here four cases of cranial and spinal dysraphism or craniorachischisis, the most severe and rare type of NTD with brief maternal history. In all these cases, the neural tissue is exposed in the region of brain as well as in the region of spinal cord to various extents. In this case series, the external features of craniorachischisis in four female fetuses (including monozygotic twins) are reported. One of the affected fetuses had associated omphalocele. 
546 |a EN 
690 |a anencephaly 
690 |a craniorachischisis 
690 |a dysraphism 
690 |a neural tube defect 
690 |a neurulation 
690 |a Human anatomy 
690 |a QM1-695 
655 7 |a article  |2 local 
786 0 |n National Journal of Clinical Anatomy, Vol 11, Iss 2, Pp 110-112 (2022) 
787 0 |n http://www.njca.info/article.asp?issn=2277-4025;year=2022;volume=11;issue=2;spage=110;epage=112;aulast=Pandurangam 
787 0 |n https://doaj.org/toc/2277-4025 
787 0 |n https://doaj.org/toc/2321-2780 
856 4 1 |u https://doaj.org/article/a74e70c1384343ee8429fb1b69bcccee  |z Connect to this object online.