Sitravatinib as a potent FLT3 inhibitor can overcome gilteritinib resistance in acute myeloid leukemia
Abstract Background Gilteritinib is the only drug approved as monotherapy for acute myeloid leukemia (AML) patients harboring FMS-like tyrosine kinase 3 internal tandem duplication (FLT3-ITD) mutation throughout the world. However, drug resistance inevitably develops in clinical. Sitravatinib is a m...
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Main Authors: | Yvyin Zhang (Author), Peihong Wang (Author), Yang Wang (Author), Yang Shen (Author) |
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Format: | Book |
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BMC,
2023-01-01T00:00:00Z.
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