HPMA Copolymer Mebendazole Conjugate Allows Systemic Administration and Possesses Antitumour Activity In Vivo
Mebendazole and other benzimidazole antihelmintics, such as albendazole, fenbendazole, or flubendazole, have been shown to possess antitumour activity, primarily due to their microtubule-disrupting activity. However, the extremely poor water-solubility of mebendazole and other benzimidazoles, result...
Saved in:
Main Authors: | Martin Studenovský (Author), Anna Rumlerová (Author), Jiřina Kovářová (Author), Barbora Dvořáková (Author), Ladislav Sivák (Author), Libor Kostka (Author), Daniel Berdár (Author), Tomáš Etrych (Author), Marek Kovář (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2022-06-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Structure-to-Efficacy Relationship of HPMA-Based Nanomedicines: The Tumor Spheroid Penetration Study
by: Júlia Kudláčová, et al.
Published: (2020) -
HPMA-Based Copolymers Carrying STAT3 Inhibitor Cucurbitacin-D as Stimulus-Sensitive Nanomedicines for Oncotherapy
by: Marina R. Tavares, et al.
Published: (2021) -
Mitochondria-Targeted Delivery of Camptothecin Based on HPMA Copolymer for Metastasis Suppression
by: Xiaoli Yi, et al.
Published: (2022) -
Micelle-Forming Block Copolymers Tailored for Inhibition of P-gp-Mediated Multidrug Resistance: Structure to Activity Relationship
by: Alena Braunová, et al.
Published: (2019) -
Treatment of intestinal helminthiasis: mebendazole only or mebendazole-pyrantel pamoate?
by: Wisman Dalimunthe, et al.
Published: (2007)