Isolation and characterization of monoclonal antibodies against human carbonic anhydrase-IX

• Main Authors: Anne E.G. Lenferink (Author), Paul C. McDonald (Author), Christiane Cantin (Author), Suzanne Grothé (Author), Mylene Gosselin (Author), Jason Baardsnes (Author), Myriam Banville (Author), Paul Lachance (Author), Alma Robert (Author), Yuneivy Cepero-Donates (Author), Stevo Radinovic (Author), Patrick Salois (Author), Marie Parat (Author), Hafida Oamari (Author), Annie Dulude (Author), Mehul Patel (Author), Martin Lafrance (Author), Andrea Acel (Author), Nathalie Bousquet-Gagnon (Author), Denis L'Abbé (Author), Alex Pelletier (Author), Félix Malenfant (Author), Maria Jaramillo (Author), Maureen O'Connor-Mccourt (Author), Cunle Wu (Author), Yves Durocher (Author), Mélanie Duchesne (Author), Christine Gadoury (Author), Anne Marcil (Author), Yves Fortin (Author), Beatrice Paul-Roc (Author), Maurizio Acchione (Author), Shawn C. Chafe (Author), Oksana Nemirovsky (Author), Joseph Lau (Author), Francois Bénard (Author), Shoukat Dedhar (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The architectural complexity and heterogeneity of the tumor microenvironment (TME) remains a substantial obstacle in the successful treatment of cancer. Hypoxia, caused by insufficient oxygen supply, and acidosis, resulting from the expulsion of acidic metabolites, are prominent features of the TME....