Recombinant Photolyase-Thymine Alleviated UVB-Induced Photodamage in Mice by Repairing CPD Photoproducts and Ameliorating Oxidative Stress

• Main Authors: Zhaoyang Wang (Author), Ziyi Li (Author), Yaling Lei (Author), Yuan Liu (Author), Yuqing Feng (Author), Derong Chen (Author), Siying Ma (Author), Ziyan Xiao (Author), Meirong Hu (Author), Jingxian Deng (Author), Yuxin Wang (Author), Qihao Zhang (Author), Yadong Huang (Author), Yan Yang (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cyclobutane pyrimidine dimers (CPDs) are the main mutagenic DNA photoproducts caused by ultraviolet B (UVB) radiation and represent the major cause of photoaging and skin carcinogenesis. CPD photolyase can efficiently and rapidly repair CPD products. Therefore, they are candidates for the prevention...