Risk of Major Congenital Malformations Associated with the Use of Japanese Traditional (Kampo) Medicine Containing Ephedra During the First Trimester of Pregnancy

• Main Authors: Aoi Noda (Author), Taku Obara (Author), Fumiko Matsuzaki (Author), Satoko Suzuki (Author), Ryutaro Arita (Author), Minoru Ohsawa (Author), Ryo Obara (Author), Kei Morishita (Author), Fumihiko Ueno (Author), Genki Shinoda (Author), Masatsugu Orui (Author), Keiko Murakami (Author), Mami Ishikuro (Author), Akiko Kikuchi (Author), Shin Takayama (Author), Tadashi Ishii (Author), Hiroshi Kawame (Author), Shigeo Kure (Author), Shinichi Kuriyama (Author)
• Format: Book
• Published: Adis, Springer Healthcare, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Japanese traditional (Kampo) medicines containing ephedra may be used to treat colds during pregnancy. There are reports that ephedrine, a component of ephedra, has a risk of teratogenicity; however, the evidence remains equivocal. Objective This study aimed to evaluate the risk...