Schaftoside inhibits 3CLpro and PLpro of SARS-CoV-2 virus and regulates immune response and inflammation of host cells for the treatment of COVID-19
It is an urgent demand worldwide to control the coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus. The 3-chymotrypsin-like protease (3CLpro) and papain-like protease (PLpro) are key targets to discover SARS-CoV-2 inhibitors....
Saved in:
Main Authors: | Yang Yi (Author), Meng Zhang (Author), Heng Xue (Author), Rong Yu (Author), Yang-Oujie Bao (Author), Yi Kuang (Author), Yue Chai (Author), Wen Ma (Author), Jing Wang (Author), Xiaomeng Shi (Author), Wenzhe Li (Author), Wei Hong (Author), Junhua Li (Author), Elishiba Muturi (Author), Hongping Wei (Author), Joachim Wlodarz (Author), Szczepan Roszak (Author), Xue Qiao (Author), Hang Yang (Author), Min Ye (Author) |
---|---|
Format: | Book |
Published: |
Elsevier,
2022-11-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Effects of diarylbutane lignans from Schisandra chinensis fruit on SARS-CoV-2 3CLpro and PLpro and their in vitro anti-inflammatory properties
by: Bin Li, et al.
Published: (2023) -
Physiologically based pharmacokinetic modelling and simulation to predict the plasma concentration profile of schaftoside after oral administration of total flavonoids of Desmodium styracifolium
by: Xue Li, et al.
Published: (2022) -
Potential inhibitors of SARS-CoV-2 (COVID 19) proteases PLpro and Mpro/ 3CLpro: molecular docking and simulation studies of three pertinent medicinal plant natural components
by: Devvret Verma, et al.
Published: (2021) -
Licorice-saponin A3 is a broad-spectrum inhibitor for COVID-19 by targeting viral spike and anti-inflammation
by: Yang Yi, et al.
Published: (2024) -
3CLpro inhibitors: DEL-based molecular generation
by: Feng Xiong, et al.
Published: (2022)