The Significance of Brain Transcranial Sonography in Burning Mouth Syndrome: a Pilot Study

Objective: Burning mouth syndrome (BMS) is a chronic disorder which is affecting mostly postmenopausal women and is characterized by burning symptoms in the oral cavity on the clinically healthy oral mucosa. The results of previous studies suggested a possible role of peripheral and/or central neuro...

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Main Authors: Iris Zavoreo (Author), Vanja Vučićević Boras (Author), Dijana Zadravec (Author), Vanja Bašić Kes (Author), Dubravka Ciliga (Author), Dragana Gabrić (Author)
Format: Book
Published: University of Zagreb. School of Dental Medicine, 2017-01-01T00:00:00Z.
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Summary:Objective: Burning mouth syndrome (BMS) is a chronic disorder which is affecting mostly postmenopausal women and is characterized by burning symptoms in the oral cavity on the clinically healthy oral mucosa. The results of previous studies suggested a possible role of peripheral and/or central neurological disturbances in these patients. The aim of this study was to analyze patients with burning mouth syndrome using transcranial sonography. Methods: By use of transcranial sonography of the brain parenchyma, substantia nigra, midbrain raphe and brain nucleus were evaluated in 20 patients with BMS (64.7±12.3 years) and 20 controls with chronic pain in the lumbosacral region (61.5±15). Statistical analysis was performed by use of Student t test with significance set at p<0.05. Results: The results of this study have shown hypoechogenicity of the substantia nigra and midbrain raphe as well as hyperechogenicity of the brain nucleus in BMS patients (p<0,05) as compared to controls. Conclusions: Altered transcranial sonography findings of the brain parenchyma, midbrain raphe and brain nucleus in patients with burning mouth syndrome might reflect central disturbances within this syndrome.
Item Description:0001-7019
1846-0410
10.15644/asc51/1/6