Role of maternal nutrition and oxidative stress in placental telomere attrition in women with preeclampsia

Background:Maternal nutrition influences the growth and development of the fetus and influences pregnancy outcome. We have earlier demonstrated altered maternal nutrition and increased oxidative stress in women with preeclampsia. Oxidative stress is known to be associated with reduced telomere lengt...

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Main Authors: Aditi A. Godhamgaonkar (Author), Deepali P. Sundrani (Author), Sadhana R. Joshi (Author)
Format: Book
Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Aditi A. Godhamgaonkar  |e author 
700 1 0 |a Deepali P. Sundrani  |e author 
700 1 0 |a Sadhana R. Joshi  |e author 
245 0 0 |a Role of maternal nutrition and oxidative stress in placental telomere attrition in women with preeclampsia 
260 |b Taylor & Francis Group,   |c 2021-01-01T00:00:00Z. 
500 |a 1064-1955 
500 |a 1525-6065 
500 |a 10.1080/10641955.2020.1869248 
520 |a Background:Maternal nutrition influences the growth and development of the fetus and influences pregnancy outcome. We have earlier demonstrated altered maternal nutrition and increased oxidative stress in women with preeclampsia. Oxidative stress is known to be associated with reduced telomere length and short telomere aggregates. Increased telomere attrition leads to increased cellular senescence and tissue ageing. Methods:The present review focuses on the role of maternal nutrition and oxidative stress in telomere attrition in preeclampsia. Results and Conclusion:Future studies need to examine the association between maternal nutritional status in early pregnancy, oxidative stress and telomere attrition in preeclampsia. 
546 |a EN 
690 |a cellular senescence 
690 |a telomere attrition 
690 |a placental aging 
690 |a preeclampsia 
690 |a oxidative stress 
690 |a Gynecology and obstetrics 
690 |a RG1-991 
655 7 |a article  |2 local 
786 0 |n Hypertension in Pregnancy, Vol 40, Iss 1, Pp 63-74 (2021) 
787 0 |n http://dx.doi.org/10.1080/10641955.2020.1869248 
787 0 |n https://doaj.org/toc/1064-1955 
787 0 |n https://doaj.org/toc/1525-6065 
856 4 1 |u https://doaj.org/article/a85eee6665a84cf38ebad48f3b8f293d  |z Connect to this object online.