Role of steroids in critically-ill sepsis patients: a review article and literature to review

• Main Authors: Mohsin Mirza (Author), Maryam Zafar (Author), Mariam Siddiqui (Author), Anum Abbas (Author), Joseph Nahas (Author), Muazzam Mirza (Author), Abubakar Tauseef (Author)
• Format: Book
• Published: Greater Baltimore Medical Center, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 2000-9666; 10.1080/20009666.2021.1964164
• Keywords: role; steroid; sepsis; review; literaure; critically ill; Internal medicine; RC31-1245
• Source: Journal of Community Hospital Internal Medicine Perspectives, Vol 11, Iss 6, Pp 825-829 (2021)

Sepsis, a life-threatening condition, commonly affecting critically ill patients, is a major cause of death worldwide. It is thus of great importance to determine the optimum management to cure this condition. This review article summarizes the role and effects of corticosteroids in the treatment of sepsis and septic shock, and to determine its mortality benefits. We used PubMed, Google scholar, Scopus, and Embase databases for literature review, and terminologies commonly searched were 'sepsis', 'septic shock', 'therapeutic use' and 'corticosteroids'. In this review article, we reviewed a total of eight different articles being done in last 10 years, relevant to the clinical outcome and effects of corticosteroids. Among those, two demonstrated improved clinical outcomes, two showed both improved clinical outcomes and decreased mortality, three showed increased adverse effects, and the remaining one showed unequivocal results.