Prognostic and predictive value of human equilibrative nucleoside transporter 1 (hENT1) in extrahepatic cholangiocarcinoma: a translational study

• Main Authors: Lenka N. C. Boyd (Author), Lynn E. Nooijen (Author), Mahsoem Ali (Author), Jisce R. Puik (Author), Jasmine Moustaquim (Author), Stephanie M. Fraga Rodrigues (Author), Robert Broos (Author), Ali Belkouz (Author), Laura L. Meijer (Author), Tessa Y. S. Le Large (Author), Joris I. Erdmann (Author), Gerrit K. J. Hooijer (Author), Michal Heger (Author), Hanneke W. M. Van Laarhoven (Author), Eva Roos (Author), Geert Kazemier (Author), Elisa Giovannetti (Author), Joanne Verheij (Author), Heinz-Josef Klümpen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Effective (neo) adjuvant chemotherapy for cholangiocarcinoma is lacking due to chemoresistance and the absence of predictive biomarkers. Human equilibrative nucleoside transporter 1 (hENT1) has been described as a potential prognostic and predictive biomarker. In this study, the potent...