Identification and Development of BRD9 Chemical Probes

• المؤلفون الرئيسيون: Ester Colarusso (مؤلف), Maria Giovanna Chini (مؤلف), Giuseppe Bifulco (مؤلف), Gianluigi Lauro (مؤلف), Assunta Giordano (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2024-03-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

The development of BRD9 inhibitors involves the design and synthesis of molecules that can specifically bind the BRD9 protein, interfering with the function of the chromatin-remodeling complex ncBAF, with the main advantage of modulating gene expression and controlling cellular processes. Here, we s...