Identification and Development of BRD9 Chemical Probes

• Autors principals: Ester Colarusso (Autor), Maria Giovanna Chini (Autor), Giuseppe Bifulco (Autor), Gianluigi Lauro (Autor), Assunta Giordano (Autor)
• Format: Llibre
• Publicat: MDPI AG, 2024-03-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

The development of BRD9 inhibitors involves the design and synthesis of molecules that can specifically bind the BRD9 protein, interfering with the function of the chromatin-remodeling complex ncBAF, with the main advantage of modulating gene expression and controlling cellular processes. Here, we s...