Identification and Development of BRD9 Chemical Probes

• Main Authors: Ester Colarusso (Author), Maria Giovanna Chini (Author), Giuseppe Bifulco (Author), Gianluigi Lauro (Author), Assunta Giordano (Author)
• Format: Bog
• Udgivet: MDPI AG, 2024-03-01T00:00:00Z.
• Fag: article
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The development of BRD9 inhibitors involves the design and synthesis of molecules that can specifically bind the BRD9 protein, interfering with the function of the chromatin-remodeling complex ncBAF, with the main advantage of modulating gene expression and controlling cellular processes. Here, we s...