Identification and Development of BRD9 Chemical Probes

• Κύριοι συγγραφείς: Ester Colarusso (Συγγραφέας), Maria Giovanna Chini (Συγγραφέας), Giuseppe Bifulco (Συγγραφέας), Gianluigi Lauro (Συγγραφέας), Assunta Giordano (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: MDPI AG, 2024-03-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

The development of BRD9 inhibitors involves the design and synthesis of molecules that can specifically bind the BRD9 protein, interfering with the function of the chromatin-remodeling complex ncBAF, with the main advantage of modulating gene expression and controlling cellular processes. Here, we s...