Identification and Development of BRD9 Chemical Probes

• Автори: Ester Colarusso (Автор), Maria Giovanna Chini (Автор), Giuseppe Bifulco (Автор), Gianluigi Lauro (Автор), Assunta Giordano (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2024-03-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

The development of BRD9 inhibitors involves the design and synthesis of molecules that can specifically bind the BRD9 protein, interfering with the function of the chromatin-remodeling complex ncBAF, with the main advantage of modulating gene expression and controlling cellular processes. Here, we s...