ADP-Mediated Upregulation of Expression of CD62P on Human Platelets Is Critically Dependent on Co-Activation of P2Y1 and P2Y12 Receptors

• Main Authors: Ronald Anderson (Author), Annette J. Theron (Author), Helen C. Steel (Author), Jan G. Nel (Author), Gregory R. Tintinger (Author)
• Format: Book
• Published: MDPI AG, 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study probed the differential utilization of P2Y1 and P2Y12 receptors in mobilizing CD62P (P-selectin) from intracellular granules following activation of human platelets with adenosine 5'-diphosphate (ADP, 100 µmol·L⁻¹) Platelet-rich plasma (PRP) was prepared from t...