Tetramethylpyrazine ameliorates acute lung injury by regulating the Rac1/LIMK1 signaling pathway

• Main Authors: Simin Min (Author), Weiting Tao (Author), Dushan Ding (Author), Xiaonan Zhang (Author), Shidi Zhao (Author), Yong Zhang (Author), Xiaojie Liu (Author), Kefei Gao (Author), Saisai Liu (Author), Li Li (Author), Min Hou (Author), Yan Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acute lung injury (ALI) is a respiratory disorder characterized by severe inflammation of the alveoli and lung parenchyma. Tetramethylpyrazine (TMP), the main active compound in Ligusticum chuanxiong Hort (LC), can protect against lipopolysaccharide (LPS)-induced ALI. Our study aimed to investigate...