A Comprehensive Review of Pegvaliase, an Enzyme Substitution Therapy for the Treatment of Phenylketonuria

Objective: To review the pharmacology, pharmacokinetics, efficacy, safety, and place in therapy of a phenylalanine-metabolizing enzyme indicated to reduce blood phenylalanine concentrations, pegvaliase injection. Data Sources: Searches of MEDLINE (1946-September 1, 2018) were conducted using the ter...

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Main Authors: Tasmina Hydery (Author), Valerie Azzopardi Coppenrath (Author)
Format: Book
Published: AboutScience Srl, 2019-06-01T00:00:00Z.
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