Rotavirus VP6 as an Adjuvant for Bivalent Norovirus Vaccine Produced in <i>Nicotiana benthamiana</i>

• Main Authors: Maria Malm (Author), André Diessner (Author), Kirsi Tamminen (Author), Markus Liebscher (Author), Timo Vesikari (Author), Vesna Blazevic (Author)
• Format: Book
• Published: MDPI AG, 2019-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Rotaviruses (RVs) and noroviruses (NoVs) are major causes of childhood acute gastroenteritis. During development of a combination vaccine based on NoV virus-like particles (VLP) and RV VP6 produced in baculovirus expression system in insect cells, a dual role of VP6 as a vaccine antigen and an adjuv...