A novel lupene derivative from Thymus capitatus possesses an apoptosis-inducing effect via Let-7 miRNA/Cyclin D1/VEGF cascade in the A549 cell line
Abstract Non-small-cell lung carcinoma (NSCLC) is a type of epithelial lung cancer accounting for about 85% of all lung cancers. In our research, a novel lupene derivative namely acetoxy-lup-5(6), 20(29)-diene (ALUP), as well as two known triterpenes; lupeol (LUP) and betulinic acid (BA) were isolat...
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Main Authors: | Nora M. Aborehab (Author), Maha M. Salama (Author), Shahira M. Ezzat (Author) |
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Format: | Book |
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BMC,
2023-10-01T00:00:00Z.
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