In Situ Gelling Ophthalmic Drug Delivery System for the Optimization of Diagnostic and Preoperative Mydriasis: In Vitro Drug Release, Cytotoxicity and Mydriasis Pharmacodynamics

• Main Authors: Pierre-Louis Destruel (Author), Ni Zeng (Author), Françoise Brignole-Baudouin (Author), Sophie Douat (Author), Johanne Seguin (Author), Elodie Olivier (Author), Melody Dutot (Author), Patrice Rat (Author), Sophie Dufaÿ (Author), Amélie Dufaÿ-Wojcicki (Author), Marc Maury (Author), Nathalie Mignet (Author), Vincent Boudy (Author)
• Format: Book
• Published: MDPI AG, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mydriasis is required prior to many eye examinations and ophthalmic surgeries. Nowadays, phenylephrine hydrochloride (PHE) and tropicamide (TPC) are extensively used to induce mydriasis. Several pharmaceutic dosage forms of these two active ingredients have been described. However, no optimal therap...