Short-term exposure to air pollution and mental disorders: a case-crossover study in New York City

There is growing evidence suggesting that exposure to air pollutants is associated with mental disorders. We investigated the impact of short-term exposures to both fine particulate matter (PM _2.5 ) and ozone (O _3 ) assessed at fine spatiotemporal resolutions on emergency room (ER) visits related...

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Main Authors: Eun-Hye Yoo (Author), John E Roberts (Author), Youngseob Eum (Author), Xiaojiang Li (Author), Lingzhi Chu (Author), Pin Wang (Author), Kai Chen (Author)
Format: Book
Published: IOP Publishing, 2022-01-01T00:00:00Z.
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Summary:There is growing evidence suggesting that exposure to air pollutants is associated with mental disorders. We investigated the impact of short-term exposures to both fine particulate matter (PM _2.5 ) and ozone (O _3 ) assessed at fine spatiotemporal resolutions on emergency room (ER) visits related to mental disorders using 475 755 records from New York City between 2010 and 2016. We assessed the short-term impact of daily air pollution exposure on ER visits using a case-crossover design with conditional logistic regression. We further tested whether the impact of PM _2.5 and O _3 varied by individuals' age, sex, and race/ethnicity, and if associations were modified by the degree of visibility of greenspace at individuals' residences. Results suggested that the relative risk of visiting an ER for mental-disorders increased by 2.78% (95% CI: 1.82%-3.76%) with a 10 $\mu\textrm{g}\,\textrm{m}^{-3}$ increase in ambient PM _2.5 concentration over a 4 day (d) moving average (lag 0-3 d) and increased by 0.71% (95% CI: 0.28%-1.15%) with a 10 ppb increase in O _3 concentration on a single day lag (lag 1 d), and that these effects were modified by age and race/ethnicity, but not by sex or surrounding greenery. Specifically, we found that age group 19-35 years old and non-Whites were more susceptible to the effects of ambient air pollution exposure. In terms of specific disorders, we found that both PM _2.5 and O _3 have an effect on ER visits for psychotic disorders, but not dementia. Our findings suggest that short-term exposure to ambient air pollution is associated with increased ER visits for mental disorders. Further research is needed to determine the underlying mechanisms by which exposure to PM _2.5 and O _3 is linked to these ER visits.
Item Description:10.1088/2752-5309/ac6439
2752-5309