A Negative Correlation Between Expression Profiles of Runt-Related Transcription Factor-2 and Cystine/Glutamate Antiporter xCT Subunit in Ovariectomized Mouse Bone

• Главные авторы: Kyosuke Uno (Автор), Takeshi Takarada (Автор), Yukari Nakamura (Автор), Hiroyuki Fujita (Автор), Eiichi Hinoi (Автор), Yukio Yoneda (Автор)
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• Опубликовано: Elsevier, 2011-01-01T00:00:00Z.
• Предметы: article
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We have previously demonstrated that glutamate (Glu) suppresses cellular proliferation toward self-renewal through a mechanism associated with the depletion of intracellular GSH after promoting the retrograde operation of the bidirectional cystine/Glu antiporter in undifferentiated osteoblastic MC3T...