The Significance of the Sulfatase Pathway for Local Estrogen Formation in Endometrial Cancer

• Main Authors: Maša Sinreih (Author), Tamara Knific (Author), Maja Anko (Author), Neli Hevir (Author), Katja Vouk (Author), Aleš Jerin (Author), Snježana Frković Grazio (Author), Tea Lanišnik Rižner (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Endometrial cancer (EC) is the most common estrogen-dependent gynecological malignancy in the developed World. To investigate the local formation of estradiol (E2), we first measured the concentrations of the steroid precursor androstenedione (A-dione) and the most potent estrogen, E2, and we evalua...