5-Azacytidine Promotes an Inhibitory T-Cell Phenotype and Impairs Immune Mediated Antileukemic Activity
Demethylating agent, 5-Azacytidine (5-Aza), has been shown to be active in treatment of myeloid malignancies. 5-Aza enhances anticancer immunity, by increasing expression of tumor-associated antigens. However, the impact of 5-Aza immune responses remains poorly understood. Here, T-cell mediated tumo...
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| Main Authors: | , , , , , , , |
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| Format: | Book |
| Published: |
Hindawi Limited,
2014-01-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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