Mining a cathepsin inhibitor library for new antiparasitic drug leads.
The targeting of parasite cysteine proteases with small molecules is emerging as a possible approach to treat tropical parasitic diseases such as sleeping sickness, Chagas' disease, and malaria. The homology of parasite cysteine proteases to the human cathepsins suggests that inhibitors origina...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Book |
| Published: |
Public Library of Science (PLoS),
2011-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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